WebNov 26, 2024 · Cisplatin is one of the commonly used anticancer drugs in clinic chemotherapy, but drug resistance is a major therapeutic obstacle for successful treatment. ... recent studies indicated an effective inhibitory effect by ginkgolic acid C17:1, with IC50 values of less than 2 μM, ... in potassium chloride-induced α-synuclein aggregates in SH ... WebSep 16, 2005 · Human neuroblastoma SH-SY5Y cells (1.5 × 10 6 per 60-mm dish) were plated and after 24 hours were treated with 4 μmol/L CDDP, 1 μmol/L paclitaxel alone, or …
Anticancer potency of copper(II) complexes of thiosemicarbazones
WebOct 23, 2024 · Cisplatin 5 µg and different concentrations (Cisplatin + CoS NPs bioconjugates (5, 10, 25, 50, 75 μg) doses were applied to SH-SY5Y neuroblastoma cell lines for 24 h. TAC, TOS and MTT tests were performed 24 h after the application. WebFrom the 35 % solution (probably in water) prepare a working stock in water and dilute it in PBS to get the designated final concentration (s); treat the cells H2O2 in PBS for 10-20 min; analyze... lowes suspended ceiling tiles
Cisplatin (Cisplatin Injection): Uses, Dosage, Side Effects
WebSH-SY5Y were deposited to the ATCC(®) in 1970 by June L. Biedler.Three important characteristics of SH-SY5Y cells should be considered when using these cells in in vitro studies. First, cultures include both adherent and floating cells, both types of … WebThe IC50 values of the two platinum derivatives varied considerably. The values for cisplatin varied between 0.022 microgram ml-1 and 0.56 microgram ml-1 and the corresponding values for carboplatin were 0.096-1.20 microgram ml-1. The range of the ratios between carboplatin IC50 and cisplatin IC50, from 1.5:1 to 4.4:1, was rather narrow. WebCisplatin 50 mg should be given once in 3 to 4 weeks. High dose of cisplatin 50 mg may cause severe neuropathy. Loss of motor nerve function may occur. Irregular liver … lowes swamp cooler motors